منابع مشابه
Pregnancy and isotretinoin therapy.
Moreover, this ratio has increased to one-third for drugs given a priority review. Because we do have specific evidence for interactions between some medications and grapefruit, the public should be updated about new drugs where this interaction may be missed. Is it sufficient that we identify these warnings and withdrawals only after they may have caused human suffering? After 20 years and hun...
متن کاملOccurrence of pregnancy and pregnancy outcomes during isotretinoin therapy.
BACKGROUND Isotretinoin, a teratogen, is widely used to treat cystic acne. Although the risks of pregnancy during isotretinoin therapy are well recognized, there are doubts about the level of adherence with the pregnancy prevention program in Canada. Our objective was to evaluate the effectiveness of the Canadian pregnancy prevention program in 4 provinces: British Columbia, Saskatchewan, Manit...
متن کاملCreatine phosphokinase values and myalgia during isotretinoin therapy
Background: Systemic isotretinoin is a very effective medication for the treatment of acne, but it has some side effects. One of its side effects is musculoskeletal problems such as increased levels of creatine phosphokinase (CPK), myalgia, and serious muscle damage such as rhabdomyolysis. The aim of this study was to evaluate the incidence of myalgia and its relationship with the elevation of ...
متن کاملHenoch-Schönlein Purpura during Isotretinoin Therapy
Received April 5, 2012, Revised May 25, 2012, Accepted for publication June 3, 2012 Corresponding author: Mutlu Cayirli, Department of Dermatology, Agri Military Hospital, Merkez, 04200, Agri, Turkey. Tel: 90-537-62076-79, Fax: 90-472-216-27-47, E-mail: [email protected] This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http...
متن کاملAngioedema due to Systemic Isotretinoin Therapy
Angioedema is the swelling of the mucosal membranes as a variant of urticaria induced by hereditary C1 esterase inhibitor enzyme deficiency, certain foods, or drugs. Herein, we report the case of a 23-year-old woman, with mild-moderate acne presenting with widespread facial angioedema on the 2nd day of systemic isotretinoin treatment. The patient had taken no drugs other than isotretinoin in th...
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ژورنال
عنوان ژورنال: Canadian Medical Association Journal
سال: 2013
ISSN: 0820-3946,1488-2329
DOI: 10.1503/cmaj.120729